Tregs相关论文
第一部分原发性皮肤黑色素瘤中表皮常驻的朗格汉斯细胞和单核来源的朗格汉斯细胞在不同时期的数目和分布目的:黑色素瘤免疫抑制性......
目的 Sarcoidosis is a systemic inflammatory disorder characterized by granulomas.Not enough evidences correlate the dera......
Aloperine attenuate mice symptoms from colitis by regulating PI3K/AKT/mTOR signaling pathway and Fox
Aloperine has been recognized with the potential capacity to treat inflammatory and allergic diseases as well as colitis......
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Aim: To induce bone marrow tolerogenic dendritic cells (TDCs) and to investigate the mechanism by which bone marrow TDCs......
Alveolar echinococcosis (AE) is a grievous zoonotic disease caused by Echinococcus multilocularis (E.multilocularis).It ......
目的：桥本甲状腺炎(Hashimotos thyroiditis,HT)是以自身甲状腺抗原反应为特点的一类疾病,关于疾病发生及发展的免疫学机制至今尚未......
目的：本研究探讨Th17和Tregs平衡失调与大鼠根尖周炎的炎症反应及牙槽骨 破坏的关系。方法：选取5周龄雄性Wistar大鼠(n=20),实验组用......
Endotoxic shock-expanded murine CD11clowCD45RB+ regulatory dendritic cells modulate inflammatory T c
Changes in the number and function of dendritic cells (DCs) have been reported to play an important role in endotoxin to......
Purpose:In this study, we analyzed the CD4+CD25+Foxp3+ Tregs expression in the cancer patients after the kidney transpla......
目的：机体的免疫系统在口腔鳞状细胞癌发生发展中发挥重要的作用。目前单一的免疫治疗药物对于患者抑制肿瘤的效率并不高，因此寻找可......
Tristetraprolin in gastric cancer cells suppresses PDL1 expression and inhibits tumor progression by
Objective The RNA-binding protein tristetraprolin(TTP)binds to AU-rich elements in the 3-untranslated region of messenge......
The dynamic modulation of a co-expression DNA vaccine containing GAD65 fragment and IL-10 gene on Tr
Objective To evaluate the effect of co-expression DNA vaccine containing GAD65 fragment and IL-10 gene in preventing you......
Expression of costimulatory molecules B7-H1, B7-H4 and Foxp3+ Tregs in gastric cancer and the clinic
Objective Immune escape plays an important role in tumor progression.In the present study, the expression of B7-H1, B7-H......
Cyclophosphamide abrogates the expansion of CD4+Foxp3+ regulatory T cells and enhances the effcacy o
Objective: Promotion of the proliferative expansion of CD4+Foxp3+ regulatory T cells (Tregs) is one of the side effects ......
目的探讨传染性单核细胞增多症（IM）患儿和传染性单核细胞综合征（IMS）患儿程序性死亡受体1（PD-1）以及调节性T细胞（Tregs）的差异。方法选择20......
银屑病是一种常见的难治性皮肤病,以过度激活的T细胞产生的异常免疫应答为主要特征。在机体免疫系统内,免疫抑制性细胞主要包括髓......
L1CAM overexpression promotes tumor progression through recruitment of regulatory T cells in esophag
Objective:L1 cell adhesion molecule(L1 CAM)exhibits oncogenic activity in tumors.However,the link between L1 CAM and the......
目的探讨人类免疫缺陷病毒(HIV)感染长期不进展者(LTNPs)接受抗逆转录病毒治疗(ART)人群与HIV进展者接受ART人群的调节性T细胞(Tre......
L1CAM overexpression promotes tumor progression through recruitment of regulatory T cells in esophag
Objective:L1 cell adhesion molecule (L1CAM) exhibits oncogenic activity in tumors. However, the link between L1CAM and t......
源于胸腺的表达转录因子Foxp3的CD4＋CD25＋调节性T细胞具有免疫调节功能，在外周免疫耐受中有重要作用，可控制异基因造血干细胞移植（allo......
Regulatory T cells(Tregs) play an important role in maintaining self-tolerance and immune homeostasis, but they also pla......
目的通过观察活性维生素D3对实验性自身免疫性肌炎小鼠是否有抑制作用,通过测量调节性T细胞(Treg)转录因子Foxp3和其相关的IL-10和......
白癜风是一种临床常见的色素脱失性皮肤黏膜疾病,以表皮基底层黑色素细胞凋亡破坏为特点,发病机制复杂,治疗手段有限.白癜风的发病......
目的:分析调节性T细胞（Regulatory T cells,Tregs）和CD8+T细胞在恶性黑色素瘤局部免疫微环境中的浸润情况,及其与预后的关系,并探讨......
目的:研究PD-1/PD-L1及相关分子表达水平在泡球蚴持续性感染中的变化特点及其与感染病灶的相关性,探讨其在泡球蚴感染中的免疫作用......
目的:RNA结合蛋白Tristetraprolin(TTP)通过结合信使RNA 3’端非翻译区的AU富集元件来降低其稳定性,从而促进靶向信使RNA的降解。......
背景结肠癌是发病率和死亡率均较高的一种恶性肿瘤。虽然这些年传统治疗手段得到了不断发展,但其五年生存率仍很低。随着细胞程序......
Depletion of CD25~+CD4~+T cells (Tregs) enhances the HBV-specific CD8~+ T cell response primed by DN
AIM: Persistent hepatitis B virus (HBV) infection is characterized by a weak CD8+ T cell response to HBV. Immunotherapeu......
目的研究瘦素(Leptin)在系统性红斑狼疮(SLE)患者中表达情况及与疾病活动度、临床和实验室指标及CD4~+CD25~+Foxp3~+Tregs的关系,......
目的探讨RA患者外周血各DCs亚群数量的变化,为进一步阐明RA的发病机制奠定基础。方法选取63例RA患者和30例相匹配的健康体检者作为......
目的探讨芬戈莫德(FTY720)影响调节性T细胞(Tregs)迁徙与抑制小鼠结肠癌发展的关系。方法灌胃给予结肠癌模型小鼠FTY720,检测Tregs......
目的观察分析人源化NOD小鼠体内CD8+CD25+T细胞的频率及功能,探讨CD8+CD25+T细胞在人源化NOD小鼠的自身免疫进程中的作用。方法采......
目的探讨调节性T细胞(Tregs)在致死型约氏疟原虫(Plasmodiumyoelii17XL,P.y17XL)感染早期的作用。方法用P.y17XL感染DBA/2、BALB/c......
目的探讨日本血吸虫(Schistosoma japonicum,SJ)感染鼠树突状细胞(Dendritic cell,DC)亚型对过敏性哮喘的抑制作用及其机制。方法......
目的研究CD4+CD25+CD127dim/-调节性T(Treg)细胞在乳癌患者和阴性对照组(纤维瘤)患者外周血中表达及意义;探索应用免疫磁珠分选技......
Metastasis is the main cause of death in cancer patients.To improve the outcomes of patients undergoing a surgery,new ad......
目的探讨乳腺癌患者外周血单个核细胞中CD4~+CD25~+CD127~(dim/-)Tregs细胞TCRB链CDR3的基因,氨基酸序列及初步结构。方法采用免疫......
目的 探讨日本血吸虫感染过程中,小鼠调节性T细胞(Tregs)及其亚群的动态变化及其在感染中的作用.方法 采用流式细胞术检测日本血吸......
目的了解乙型肝炎患者外周血Tregs水平并探讨其在乙型肝炎病人发病机制中的作用。方法采用流式细胞术检测乙型肝炎患者及对照组外......
源于胸腺的表达转录因子Foxp3的CD4+CD25+调节性T细胞具有免疫调节功能,在外周免疫耐受中有重要作用,可控制异基因造血干细胞移植(......
肿瘤干细胞(cancer stem cells,CSCs)是肿瘤疾病治疗中的关键概念之一,近年来越来越引起研究者们的关注.由于CSCs具有高度的抵抗力......
目的 探讨在胆囊癌(GC)中吲哚胺2,3-双加氧酶(IDO)表达和调节性T细胞(Tregs)的浸润及其与临床预后的关系.方法 应用免疫组织化学技......
目的探讨粪菌移植对过敏性哮喘幼鼠的影响及其机制。方法孕2周的BALB/c小鼠随机分为三组:正常对照组,哮喘模型组和粪菌移植组。待......
为探讨调节性T细胞（Tregs）对伯氏疟原虫感染所致鼠脑型疟发生和感染结局的影响机制，用伯氏疟原虫ANKA株分别感染对照组和抗CD25单克隆......
AIM To investigate the effect of chymase inhibitorTY-51469 in the therapy of inflammatory bowel diseaseand the underlyin......
目的通过对多发性骨髓瘤（MM）患者外周血淋巴细胞亚群的检测以评价MM患者机体的免疫功能状态。方法采用流式细胞术检测36例MM患者和25......
